Abbreviated pretransfusion testing
نویسندگان
چکیده
منابع مشابه
Pretransfusion testing and transfusion of uncrossmatched erythrocytes.
191 January 2015 B LOOD transfusion is the most frequent procedure performed during hospital admissions1 and many transfusions are administered in the perioperative period, often on a time-sensitive basis. In this clinical commentary, key points related to pretransfusion testing are reviewed with an emphasis on the electronic crossmatch, as well as the use of uncrossmatched erythrocytes in situ...
متن کاملRed cell genotyping and the future of pretransfusion testing.
Over the past 20 years the molecular bases of almost all the major blood group antigens have been determined. This research has enabled development of DNA-based methods for determining blood group genotype. The most notable application of these DNA-based methods has been for determining fetal blood group in pregnancies when the fetus is at risk for hemolytic disease of the fetus and newborn. Th...
متن کاملInterference of daratumumab with pretransfusion testing, mimicking a high-titer, low avidity like antibody
Daratumumab is a monoclonal immunoglobulin against CD38 and has been approved for treating patients with refractory multiple myeloma. The presence of daratumumab in the sera can interfere with pretransfusion testing due to the weakly expression of CD38 on red cells. The reactivity could be mistaken as autoantibody (if autocontrol is positive) or alloantibody (if autocontrol is negative). We pre...
متن کاملDuffy and Kidd Genotyping Facilitates Pretransfusion Testing in Patients Undergoing Long-Term Transfusion Therapy
OBJECTIVE Conventional serologic typing of red blood cell systems other than ABO and RhD can be inaccurate and difficult to interpret in patients who have recently undergone blood transfusion. While molecular-based assays are not used routinely, the usefulness of genotyping was investigated in order to determine patients who may benefit from this procedure. MATERIALS AND METHODS Blood samples...
متن کاملEvaluation of an abbreviated protocol for cytomegalovirus pp65 antigenemia testing.
The cytomegalovirus antigenemia assay remains a useful tool for monitoring reactivation among transplant recipients. In this study, we compared protocols using direct lysis of small-volume, whole blood (WB) samples vs peripheral blood leukocyte (PBL)-enriched fractions. Of 363 evaluable samples, 51 (14.0%) were positive by one or both methods. Sensitivity, specificity, and negative and positive...
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ژورنال
عنوان ژورنال: Transfusion
سال: 1986
ISSN: 0041-1132,1537-2995
DOI: 10.1046/j.1537-2995.1986.26386209371.x